.png){kind=small}
Hi all! Please sign up for and attend a zoom meeting OR comment your analysis.
If you can, respond to others' comments to create a more engaging environment. The comments should be insightful and more than just a few sentences long. Those who would like to attend a zoom meeting instead of commenting in this thread can sign up through the sheet attached below. Remember only one of the two (comment or attend meeting) is required to gain participation credit.
Zoom discussions give an opportunity for pre-meds to network while discussing medical topics live! Don't miss out on this!
This article was an interesting read. I think scientists should stay open minded when conducting research, to draw inferences and make connections with other medical issues that can be solved. In addition, researchers should be willing able to adapt different techniques and approaches if the results of their study are not what are looking for and this paper demonstrated exactly that. Firstly, the fact that nuclear membrane protein 1 (NEMP1) is not widely studied in humans but can be studied in animals using different animal models such as frogs, roundworms, zebrafish, fruit flies and mice indicates an alternative approach to study human diseases in animal models using genetic techniques. Moreover, the results of this study were fascinating as the researchers investigated the role of missing gene (NEMP1) leading to poor egg development in fruit flies, and further measured the stiffness of the egg’s nuclear envelope using atomic force microscopy. I think it is important to further investigate variants in this gene (NEMP1) using CRISPR gene-editing technique to study associations between mutations in NEMP1 and their effect on early menopause and infertility in humans. It is suggested that researchers would like to explore fertility issues linked to mutations in NEMP1 to establish a causal link between NEMP1 and infertility. However, I think researchers can gain better insight by studying the correlation between mutations in NEMP1 gene and its impact on egg’s nuclear envelope stiffness. In conclusion, I think scientists can potentially solve human infertility issues by using CRISPR-Cas9 gene editing technique in knock-out mice models to study mutations in NEMP1 gene variants to potentially fix and restore NEMP1 genes that can help support egg’s nuclear envelope stiffness.